MBL2 and systemic sclerosis: In line with this, MBL deficiency was rare in diffuse compared to limited SSc patients or controls (2 (9%) vs. 36 (39%) vs. 25 (28%), P = 0.02), as were low-producing MBL2 genotypes (1(4%) vs. 17 (25%) vs. 18 (20%), P = 0.1).