However, SLC3A2 was recently shown to be induced in human umbilical vein endothelial cells exposed to lipid oxidation products derived from oxidized low-density lipoproteins [77], SLC3A2 and SLC1A4 (amino acid transporters) were induced in HepG2/C3A cells in response to cysteine deprivation [78], and SLC1A1 (a cysteine transporter) was induced by tBHQ and sulforaphane in rat glioma cells [79]. This evidence concerns the gene SLC1A4 and central nervous system cancer.