KLK3 and neoplasm: The clinicopathological variables pT-stage (p<0.001), preoperative PSA value dichotomized at 10 ng/dL (n = 221, p<0.001), Gleason score (p<0.001), tumor size dichotomized at 20 mm (n = 285, p<0.001), perineural infiltration (PNI) (no = 134, p<0.001), positive surgical margins (PSM) (n = 286, p = 0.041), positive surgical circumferential margin (n = 154, p<0.001), positive surgical apical margin (n = 210, p = 0.04), and vascular infiltration (n = 43, p<0.001) were all significantly correlated to BFFS in the univariate survival analyses (Table 1).