ABCB1 and neoplasm: Among the relapsed patients, 19 of the 24 (79%, P<0.001) of the biopsied samples showed significant increases of Wnt5A expression (Figures 8A, 8D & 8G), and 21/24 (88%, P<0.001) of the tumor biopsies also showed a significant upregulated ABCB1 expression after chemotherapy (Figures 8B, 8E & 8H).