Compared with patients without renal end point, patients with renal end point were found to have a younger age, more female subjects, higher prevalence of DM and hypertension, higher systolic blood pressure, lower BMI, higher prevalence of advanced CKD stage, lower albumin, lower hemoglobin, lower baseline eGFR, lower calcium, higher phosphate, higher CaXP product, higher uric acid, higher urine protein-to-creatinine ratio, and higher prevalence of ACEI and/or ARB use. The gene discussed is ALB; the disease is hypertensive disorder.