CASP9 and triple-A syndrome: The fold change in gene expression between untreated and AAA treated cells after 72 hours was calculated and an increment in the expression of caspase-9 from 1.0 to 1.24 (P < 0.05) with a concomitant increase in the level of caspase-3 which is the executioner caspase, from 1.0 to 1.9 (P < 0.01).