Protein concentrations increased to 89, 97 and 128 μg/mL for treatments that received 1000, 2000 and 4000 mg/L of CF, respectively; this is similar to previously reported levels for DHM-1 in the absence of CF, and in the presence of CF at 500 mg/L (Shan et al. [2010a]). The gene discussed is CFTR; the disease is cystic fibrosis.