To conclude, among the clinic-pathological factors in the present study, age, tumour size, histological type, tumour stage, tumour margin, presence of lymphoid infiltrate and necrosis, lymph node metastasis, and Ki-67 positivity did not show statistically significantly correlation with CK5 and EGFR; however tumour grade shows statistically significantly correlation with CK5 only but not with EGFR. This evidence concerns the gene MKI67 and neoplasm.