TNFRSF1B and neoplasm: The here described impaired immune regulatory capacity of TNFR2-deficient MDSC might contribute to the reported higher susceptibility of TNFR2-deficient mice to pathophysiological consequences of sepsis [23], to impaired tumor growth [24], to failure of immunoparalysis after sublethal sepsis [25], and to the reported protection from sepsis-induced mortality by LPS pre-treatment [26,27].