It is of notice that SiHa tumors, which had the most robust effect in accumulation of myeloid cells in lymphoid tissues and recruitment to the tumor, displayed higher expression of IL-8 and significantly higher expression of CXCL1 in vivo than in vitro, indicating a potential role for these chemokines in the mechanism of action of SiHa tumors. This evidence concerns the gene CXCL1 and neoplasm.