As such, rather than examining the relative proportions of eosinophils versus basophils in these colonies of nascent eosinophils and basophils of mixed granulation (which one also sees in liquid cultures), we have focused on PB Eo/B CFU (and thus, HHP) production after TSLP stimulation, providing novel evidence that TSLPR engagement on PB CD34+ cells has the capacity to enhance Eo/B lineage priming of myeloid progenitors, increasing the likelihood of development of allergic eosinophilic/basophilic inflammation, in addition to disease maintenance or progression. The gene discussed is CD34; the disease is inflammation.