Consistent with our study, Winckler et al. and Bagwell et al. reported no association of HNF-4α polymorphisms (including rs1884613) with T2D in Scandinavians and Caucasian Americans [11, 18], although several other studies found the significant association with risk of T2D in the Finnish population [16], the Ashkenazi Jews [15], the Mexican Americans [21], and the Norwegians [17]. This evidence concerns the gene HNF4A and type 2 diabetes mellitus.