NF1 and malignant peripheral nerve sheath tumor: In the UCLA dataset, patients with NF-1 developed MPNST an average of 10.3 years earlier than patients without NF-1.Similar to the UCLA dataset, the meta-dataset indicated that patients with NF-1 developed MPNST at a significantly younger age than patients without NF-1 (median 28 vs. 41 years old, p < 0.0001).