The findings of this study are in accordance with this, as we found that AMDC were being activated to express costimulatory markers early after infection, that correlated with induction of high levels of IAV-specific CD8+ T cell proliferation and IFNγ production in draining lymph nodes at day 4 p.i. (Wikstrom, Stumbles, unpublished observations). This evidence concerns the gene CD8A and infection.