Some evidence support this hypothesis including the response to steroids therapy, the finding of elevated levels of autoantibodies or circulating immune complexes (CIC) in the serum of some patients with MD against inner ear antigens and the association of allelic variants of MHC class I polypeptide-related sequence A (MICA) and Toll-like receptor 10 (TLR10, rs11096955) gene with hearing loss progression in patients with MD [7], [8]. Here, TLR10 is linked to Menkes disease.