In agreement with a role for TCTP in cell growth and proliferation, this protein is overexpressed in tumor cells and its inhibition by antisense or siRNA promotes apoptosis or, in other cases, induces the reorganization of cells into specific structures when the malignant phenotype has been suppressed (i.e., in MCF-7 and T47D breast cancer cells) [14]. Here, TPT1 is linked to neoplasm.