Atopic dermatitis (AD) is chronically relapsing, non-contagious, and exudative; it typically manifests as pruritic dermatosis accompanied by perivascular infiltration of T-helper (TH1/TH2)-lymphocytes, mast cells, and immunoglobulin-E (IgE) [1], [2]. The gene discussed is IGHE; the disease is Alzheimer disease.