On day 14, no significant differences in the p-STAT3 level was found among the four groups (p-STAT3: Nicotine 0.013±0.003 vs Myocarditis 0.011±0.002 vs Methyllycaconitine 0.010±0.003 vs Normal 0.010±0.002, p>0.05) (Figure 5). The gene discussed is STAT3; the disease is myocarditis.