The analyses revealed that pretreatment serum MIP-3α and cystatin A levels were independent prognostic factors of OS and DMFS of NPC patients; serum posttreatment MIP-3α and cystatin A levels were independent prognostic factors of LRFS; and serum posttreatment MIP-3α level was also an independent prognostic factor of OS (Table 5). The gene discussed is CSTA; the disease is nasopharyngeal carcinoma.