On the other hand, four proteins (Endoglin, Nox4, Flt-1 and Calretinin) were positively correlated (Figure 3C) and two proteins (AnnexinXI and PlGF) were inversely correlated with the severity of term preeclampsia (P<0.05, R value≥0.4) (Figure 3D). This evidence concerns the gene NOX4 and preeclampsia.