HGF and preeclampsia: In term preeclampsia, IL-3 signaling and natural killer cell signaling which are related with placenta immune response, HGF signaling which is associated with trophoblast invasion [47], FGF signaling which is associated with angiogenesis, and mTOR signaling which regulates the invasive differentiation of human trophoblasts may be involved in the first stage of term preeclampsia.