In term preeclampsia, IL-3 signaling and natural killer cell signaling which are related with placenta immune response, HGF signaling which is associated with trophoblast invasion [47], FGF signaling which is associated with angiogenesis, and mTOR signaling which regulates the invasive differentiation of human trophoblasts may be involved in the first stage of term preeclampsia. This evidence concerns the gene MTOR and preeclampsia.