Finally, levels of IL-2 (ANOVA p = 0.0002), sCD40L (ANOVA p = 0.001), FGF-2 (ANOVA p = 0.0038) (Figure 1, panels c–e), generally increased from HC to T1D-N to T1D-H, but only pairwise differences for HC vs. T1D-N and HC vs. T1D-H reached significance. Here, CD40LG is linked to type 1 diabetes mellitus.