We observed that LEF-1 protein expression correlated with Bcr-Abl kinase activity in one CP CML sample (CML-6), less so in two other CP samples (CML-7 and CML-14) and not at all in the BP CML sample (CML-04-01). Here, LEF1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.