To date, in addition to α-synuclein (SNCA), parkin (PARK2), UCH-L1 (PARK5), PINK1 (PARK6), DJ-1 (PARK7), LRRK2 (PARK8), and ATP13A2 (PARK9), there are also GBA, VPS35, EIF4G1, PARK16 which have been isolated to be responsible for PD based on family based linkage analysis. Here, PRKN is linked to Parkinson disease.