Moreover, a study carried by Dranka et al. indicated that diapocynin (5,5’-dehydrodiacetovanillone) which is a synthetic compound conversed form Apocynin (4-hydroxy-3-methoxyacetophenone) could prevents early PD symptoms in the LRRK2 p.R1441G transgenic mouse. This evidence concerns the gene LRRK2 and Parkinson disease.