CD8A and Autoimmunity: In addition, in this study we did not explore other potential mechanisms that can trigger MS autoimmunity such as molecular mimicry consisting of a cross-reaction between EBV and CNS self-antigens [11], bystander damage due to a dysregulation of EBV infection within the brain [22] and accumulation of EBV infected autoreactive B cells in the CNS related to a decrease in systemic CD8 T cell control of EBV infection [3].