HSD17B12 and breast neoplasm: Overexpression of HSD17B12 was recently associated with COX2 (1q31) overexpression in breast carcinomas [47], and in our cohort, HSD17B12 gains were detected in association with COX2 gains, which may indicate a new 1q31/11p11 co-amplification pattern in ER-negative high-grade breast tumors.