ESR1 and breast carcinoma: Given that androgen receptor (AR) is widely expressed in various breast cancer types [31] and leaning on our findings that HMGCS2+/AR+/ER-/PR- phenotype is highly frequent in both ADCIS and IAC subgroups (Figure 6A, Tables S3 and S4), we calculated the frequency of this four-protein signature in non-apocrine Pantomics dataset and revealed only 7 samples (3,5%) with a combination of HMGCS2+/AR+/ER-/PR- (Table S5, corresponding rows are highlighted by Thick Box Border).