ER stress was activated by Tubeimoside-1, a triterpenoid saponin extracted from Bolbostemma paniculatum, with an increased expression of DDIT3 in human cervical carcinoma cells [29], while our previous data indicated that ATSE selectively suppressed mRNA expression of many ER stress-related genes in SMMC-7721 cells, especially of Hyou1, Hsp90aa1, Sec63, Dnajb11, Grp78, and Hspa9. This evidence concerns the gene HSPA5 and cervical carcinoma.