The implication of Miro in the mitochondrial quality control process directed by the PINK1/Parkin pathway and in PD pathogenesis opened up new directions for understanding the regulation and function of Miro in the nervous system, and raised the possibility that dysfunction of Miro may be broadly involved in the pathogenesis of other neurological disorders, where aberrant mitochondrial distribution, morphology, and function have been observed early in the disease process. Here, PINK1 is linked to Parkinson disease.