PINK1 and Parkinson disease: In a Drosophila model of PD associated with loss of function of the mitochondria-localized Pten-induced kinase 1 (PINK1), reduction of function of Miro as well as components of the transport machinery effectively rescued the degenerative phenotype in dopaminergic neurons seen in PINK1 mutant, suggesting that at least in this setting altered mitochondrial transport contributes to PINK1 pathogenesis (Liu et al., 2012).