ACTG1 and deafness: Of them, three were novel missense mutations (p.G38D in COCH, p.E316K in ACTG1, and p.P164R in POU4F3), one was a novel in-frame indel mutation (c.2036-2038delAGG in WFS1), and two were known deafness-causing mutations that have been previously reported (p.R653C in WFS1 and p.D572N in TMC1).