The previous studies showed a weak but significant correlation with the rs2275913 IL-17A promoter polymorphism in Norwegian patients with RA (Nordang et al. 2009) and the association of the rs3804513 IL-17A (A52053197T, A > T) gene polymorphism with radiographic progression in Japanese patients with early RA (Furuya et al. 2007). The gene discussed is IL17A; the disease is rheumatoid arthritis.