First, using microarrays, PIM1 and especially PIM2 genes, but not PIM3, were found to be significantly overexpressed (FDR<0.05) in tumoral samples from 38 PTCL patients compared with 6 reactive lymph nodes (Figure 1A). The gene discussed is PIM3; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.