This preliminary finding, along with the fact that ALCL cell lines are the most sensitive to the pan-PIMi ETP-39010, led us to hypothesize that the ALK - STAT3 - PIM2 pathway could be important for ALCL survival, at least in ALK+ ALCL, since ALK is a well-known STAT3 activator [5], [6], and STAT3 has been extensively described to increase PIM2 expression [13], [14]. The gene discussed is STAT3; the disease is anaplastic large cell lymphoma.