In recent years, CH or CEP has been reported to induce apoptosis of human leukemia cell line and hematoma cell line [20], decrease the activation of GST-π and NF-κB, and increase the activation of DNA Topo II to reverse MDR, suggesting that the reversing effect of CH involves multimechanisms. The gene discussed is NFKB1; the disease is cyclic hematopoiesis.