CRP and obesity due to melanocortin 4 receptor deficiency: Very recent epidemiological studies reported that increased levels of CRP correlated with depressive symptoms and abdominal obesity (Alvarez et al., 2013; Daly, 2013; Wium-Andersen et al., 2013) and other clinical works have found CRP to be the most consistent marker of the obesity-depression association (van Reedt Dortland et al., 2013a,b).