In greater detail, correlation analyses of individual cytokines revealed significant inverse correlations between the SLEDAI and inducible amounts of IL-6, IL-9, IL-17A, IFN-γ, IP-10, MIP-1α, MIP-1β, TNF-α, and VEGF of TLR9-activated SLE B cells (Figure 3B). The gene discussed is TNF; the disease is systemic lupus erythematosus.