However, no statistically significant differences of TNFAIP2 expression were observed between CC, CT and TT genotypes in ESCC tissue specimens (CC and CT: 0.0517±0.0207 [n = 8] vs. TT: 0.0566±0.0163 [n = 10], P = 0.172). The gene discussed is TNFAIP2; the disease is esophageal squamous cell carcinoma.