Likewise, confirming mRNA data, Cx43 expression (scores 1–3+) was associated with significantly longer RFS in the whole patient cohort (p = 0.026) (Fig. 4d–f) and in grade 2 tumors (p = 0.032); and it correlated positively with HR levels (ρ = 0.23) and negatively with tumor grade (ρ = −0.22). Here, GJA1 is linked to neoplasm.