NR4A1 and neoplasm: Medium to high Cx32 levels (scores 2–3+) showed a significant negative correlation with RFS in the whole cohort (p = 0.033) (Fig. 4i) and in Lumina B-Her2 positive tumors (p = 0.025); and correlated positively with tumor grade (ρ = 0.34), the presence of necrosis (ρ = 0.19), NPI (ρ = 0.28), mitotic index (ρ = 0.27) and Ki67 expression (ρ = 0.21) and negatively with hormone receptor levels (ρ = −0.3).