We compared the serum levels of CA19-9, CA125, FER, CA242, CEA, CA15-3, β-HCG, AFP, NSE, PSA, f-PSA and HGH associated with pancreatic cancer, and found that simultaneous analysis of them was important for the diagnosis of pancreatic cancer. The gene discussed is CEACAM5; the disease is familial pancreatic carcinoma.