EIF5A2 and non-small cell lung carcinoma: In order to discover the mechanism by which GC7 enhanced cisplatin sensitivity, we transfected eIF5A-2 siRNA into A549 and NCI-H1299 cells to interfere with eIF5A-2 expression, and found that eIF5A-2 expression was significantly inhibited in both NSCLC cell lines (Figure 3A).