Similarly, Msi proteinexpression was higher in luminal, HER2+ breast cancer lines (BT474, SKBR3 inFigure 2D) compared with basal HER2–breast cancer lines (brain and bone metastatic derivatives of MDAMB231, 231-Brain and231-Bone, and SUM159 in Figure 2D). The gene discussed is ERBB2; the disease is breast carcinoma.