Multiple independent HNF1B associations have now been reported for the lead SNPs in prostate cancer (in introns 1 and 4) (12), while associations are limited to a single peak in intron 3 for the serous ovarian cancer subtype, and a single peak in intron 1 for the clear cell ovarian cancer subtype (11). This evidence concerns the gene HNF1B and ovarian serous adenocarcinoma.