SLC4A7 and Familial prostate cancer: In addition to CA9, CA12 and CA14 genes have been recently reported to show upregulation in breast, colon, liver, and two lung (adenocarcinoma, squamous cell carcinoma) cancers (but not in prostate cancer), with two HCO3− transporters, NBC2 (SLC4A5) and NBC3 (SLC4A7), also being upregulated in colon, liver, and two lung cancers types analyzed [60].