The number of transition cells along Bowman’s capsule increased significantly in both strains with experimental glomerular disease, although the magnitude of increase was greater in SM22α -/- mice at day 7 (6.35 ± 0.34 vs. 4.79 ± 0.28 PAX2+/Synaptopodin+ cells/mm of Bowman’s capsule, P <0.01 vs. +/+), and day 14 (8.38 ± 0.60 vs. 6.56 ± 0.46, P <0.05 vs. +/+) (Figure 2B). Here, PAX2 is linked to glomerular disorder.