In some cancer cell lines, depletion of TACC3 induces postmitotic cell cycle arrest or mitotic cell death.15, 16, 17, 18, 19 TACC3 deletion was also shown to result in a massive apoptotic regression of mouse thymic lymphoma in vivo without any overt abnormalities in normal tissues.21 Therefore, we tested the effect of SNIPER(TACC3) on the cell viability of cancer cells. This evidence concerns the gene TACC3 and cancer.