Theileria-infection of Jed 4 macrophages (V: Jed4p18) induces both adam19 and mmp9 expression and appears to repress that of timp3. Conversely, ectopic expression of Flag-Δ169-c-Jun leads to a dampening of adam19, a reduction in mmp9, and de-repression of timp3 expression. The gene discussed is ADAM19; the disease is infection.