Treatment with B1-, B2-, B3- and Rosi- treated groups significantly decreased the mRNA level of PEPCK, G6Pase, SREBP1c, FAS and apo C-III, while increased the hepatic adiponectin mRNA level compared with the HF group (p < 0.05, p < 0.05, p < 0.01, p < 0.01, respectively). The gene discussed is PCK2; the disease is hydrops fetalis.