Total infarct volume was not different between genotypes at either 6 h (P = 0.294) or 72 h (P = 0.722) post-stroke, but was reduced in Nox2 KO mice at 24 h post-stroke compared to Nox2 WT controls (P<0.01; Fig 1A) using H&E-stained sections. The gene discussed is CYBB; the disease is stroke disorder.