At 24 h Nox2 KO mice (15.07±6.98 mm3) exhibited significantly less damage than Nox2 WT control mice (35.57±9.53 mm3, P<0.01), but by 72 h post-stroke, there was again no difference in infarct volumes between genotypes (Nox2 WT 28.77±14.14 mm3, Nox2 KO 20.92±9.28 mm3, P = 0.248). This evidence concerns the gene CYBB and stroke disorder.