CYBB and Stroke: By 72 h post-stroke, no difference in blood vessel density in the ipsilateral compared to the contralateral cortex was observed in either Nox2 WT (97.4±6.5%, P = 0.251) or Nox2 KO (105.6±6.7%, P = 0.363) mice, however there was a difference between genotypes (P<0.05; Fig 8B).