PDCD4 and cancer: Some of these target genes like HOXC8, HOXA7, HOXB7, LRP1B, p27 (regulated by mir-196a2), IRAK1, CARD10 (targets genes of mir-146), SOX6, PDCD4 (target genes of mir-499), and PABC1 (regulated by mir-423) (http://www.microrna.org/) are deregulated in many cancers [14].