Tumour and spleen concentrations of interferon-γ (IFN-γ) and interleukin-12 (IL-12) were all significantly elevated for the pEEVGmCSF-b7.1 treatments compared with untreated (P<0.001), pGT141GmCSF-b7.1 (P<0.001) and all other groups analysed. Here, IFNG is linked to neoplasm.