Splenic and tumour CD19+ (P<0.001), DX5+/CD3+ (P<0.01), DX5+/CD3− (P<0.01), CD11c+ (DCs) (P<0.001), F4/80 (P<0.001) and CD8+ (P<0.001) cells were all significantly higher for the pEEVGmCSF-b7.1-treated mice than for untreated animals. This evidence concerns the gene ITGAX and neoplasm.