ZNF282 and esophageal squamous cell carcinoma: 1A-C)and we semi-quantitatively evaluated nuclear expression of ZNF282 in ESCC and normal esophagus. The overexpression of ZNF282 was more frequent in ESCC than in normal epithelium with a statistical significance (47.2% vs 5.7%, p<0.001, Supplementary Table 1). The associations between ZNF282 expression and clinicopathologic variables are shown in Table 1.