COQ2 and multiple system atrophy: Recently, a homozygous mutation p.M128V-V393A/p.M128V-V393A (referred to by Tsuji and colleagues as p.M78V-V343A/p.M78V-V343A) and compound heterozygous mutations p.R387X/p.V393A (referred to by Tsuji and colleagues p.R337X/p.V343A) in the coenzyme Q2 4-hydroxybenzoate polyprenyltransferase gene (COQ2; OMIM 609825) were identified in affected members of two unrelated Japanese families with MSA [4].